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VS 2019 Changing excel cell color using vb.net

hello guys i asked this question before but i just don't seem to find an answer can someone please tell me what i'm doing wrong in my code because even while i tried every methode on the internet no change is ever made on my excel file. my code for changing the color of a cell on an existing excel file but eventhough i run it no changes are made on the excel file in the textbox1

Code:

Private Sub Button1_Click(sender As Object, e As EventArgs) Handles Button1.Click
        Dim ws1 As Microsoft.Office.Interop.Excel.Worksheet
        Dim xlApp As New Microsoft.Office.Interop.Excel.Application
        ws1 = xlApp.Workbooks.Open(TextBox1.Text).Worksheets(ComboBox1.SelectedItem)
        Dim rangeToFormat As Excel.Range
        rangeToFormat = ws1.Cells(6, 5)
        rangeToFormat.Interior.Color = ColorTranslator.ToOle(Color.Red)

    End Sub

    Private Sub Button2_Click(sender As Object, e As EventArgs) Handles Button2.Click
        Dim xlworkbook As Excel.Workbook
        Dim xlWorkSheet As Microsoft.Office.Interop.Excel.Worksheet
        Dim xlApp As New Microsoft.Office.Interop.Excel.Application
        OpenFileDialog1.ShowDialog()
        TextBox1.Text = OpenFileDialog1.FileName

        xlworkbook = xlApp.Workbooks.Open(TextBox1.Text, 0, True)

        For Each xlWorkSheet In xlApp.Sheets
            ComboBox1.Items.Add(xlWorkSheet.Name)
        Next
    End Sub

my code asks the user to choose an excel file, choose the worksheet that wants to work on and then click on a button to change the color of the cell(6,5) and other cells that i didn't add here to make my code easier to undrestand. thank you sooo much guys on advanced.

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